High density 5.25″ disks have much the same capacity as 8″ double density disks, and they operate at the same data rate. A 5.25″ FDD typically has a few more tracks than an 8″ FDD.
This means that a floppy disk controller expecting to see an 8″ disk drive can potentially be fooled into working with an HD 5.25″ drive. This can be very handy if you don’t have an 8″ drive or if you want a more compact setup. This trick seems to work ok with a real HD drive or with a gotek/flashfloppy. 8″ disk images can be written to HD 5.25″ media without alteration using Greaseweazle, for example.
There are a few small issues. The first is the 8″ drive interface is usually 50 pins and the 5.25″ interface is usually 34 pins. The disk controller may have both interfaces (eg the Jade DD and the 16FDC) but not always (eg the Pulsar Little Big Board only has a 50 pin interface). If there is no 34 pin interface, then an adapter will be required. The 50 pin interfaces vary a bit, so a specific adapter may be required.
The second is that 8″ drives can detect whether a drive is single or double-sided and tell the host. The operating system driver may exploit this information (eg Jade DD CP/M) so there may need to be a way to fake this. For systems that use only single sided or only double-sided disks the signal can be tied appropriately otherwise a switch may be required – and if there are different drives in the system then it may be necessary to take the signal low through a diode from the drive select line.
Third is that 8″ drives typically produced a ready (RDY) signal. Without this signal, a host may just hang. This signal is available on many drives and can usually be setup on a gotek/flashfloppy but it may not be connected on the 34 pin interface. This can be overcome by connecting pin 34 on the 34 pin interface to the appropriate pin on the 50 pin interface.